A deconvolved wide-field fluorescence microscope image of a human U20S cancer cell. The microtubules of the cytoskeleton/spindle are fluorescing green. The blue blobs are centromeres stained with human CREST autoantiserum. The red is INCENP, a protein that regulates and targets Aurora B protein kinase, which is involved in the polymerisation /depolymerisation of microtubules during mitosis.